Obstetric factors related to perinatal brain injury

Christopher S. Ennen, Ernest M. Graham

Research output: Chapter in Book/Report/Conference proceedingChapter


Labor and delivery are the culminating events of the maternal-fetal relationship. Although the outcome for mother and child is favorable in the majority of cases, events may occur during parturition that affect the future neurological status of the fetus. In this chapter, we will review the definitions, incidence, and pathophysiology of neonatal encephalopathy and cerebral palsy, examine the impact that labor and delivery have on the fetus, review the methods used to evaluate for fetal compromise during labor and neonatal markers that predict brain injury, and examine the potential interventions to reduce the risk of perinatal brain injury.

Original languageEnglish (US)
Title of host publicationMaternal Influences on Fetal Neurodevelopment
Subtitle of host publicationClinical and Research Aspects
PublisherSpringer New York
Number of pages17
ISBN (Print)9781603279208
StatePublished - Dec 1 2010


  • Cardiotocography
  • Hypoxic ischemic encephalopathy
  • Metabolic acidosis
  • Periventricular leukomalacia
  • Sentinel event

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Obstetric factors related to perinatal brain injury'. Together they form a unique fingerprint.

Cite this