Observations of periwound skin protection in venous ulcers: A comparison of treatments

Susan M. Hunter, Diane Langemo, Patricia Thompson, Darlene Hanson, Julie Anderson, In Eui Oh, Rolf Paulson, Dan Rustvang, Seth Dorman, David L. Roth

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


OBJECTIVE: The objective of this study was to examine the effectiveness of 2 products on venous ulcer periwound skin. DESIGN: This was a descriptive comparative study. SETTING: An outpatient wound care clinic in a rural Midwestern area of the United States. PARTICIPANTS: Participants included a retrospective group of 50 patients and a prospective group of 28 patients. INTERVENTION: The intervention compared the experimental product (Remedy Nutrashield; Medline Industries, Mundelein, Illinois) versus Cavilon Moisturizing Lotion (3M, St Paul, Minnesota). OUTCOMME MEASURES: The mean outcome measures were a decrease in periwound and ulcer size. MAIN RESULTS: For the periwound size, the estimated rates of change were as follows: 0.092 (SE, 0.021) cm/d and -0.026 (SE, 0.014) cm/d for products B and A groups, respectively. The decrease for the experimental group was significantly greater than the attenuated decrease for the retrospective cases (t297 = -2.57, P =.01), and the decrease for product B group was also significantly different from zero (t76 = -4.34, P <.0001). For the ulcer size model, the estimated rates of change were -0.272 (SE, 0.102) cm2/d and -0.130 (SE, 0.067) cm2/d for the experimental and retrospective groups, respectively. The rate for the experimental group was significantly less than zero (t76 = -2.67, P =.009), but there was no significant difference between prospective and retrospective cases in the rates of reduction in ulcer size (t308 = -1.16, P =.25). CONCLUSION: The results of this study illustrate how the integrity of the periwound skin may be an important determinant in decreasing periwound and ulcer size.

Original languageEnglish (US)
Pages (from-to)62-66
Number of pages5
JournalAdvances in Skin and Wound Care
Issue number2
StatePublished - Feb 2013


  • Periwound
  • Skin protectant
  • Venous ulcer

ASJC Scopus subject areas

  • Dermatology
  • Advanced and Specialized Nursing


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