Obesity and kidney disease: Hidden consequences of the epidemic

On behalf of the World Kidney Day Steering Committee

Research output: Contribution to journalArticlepeer-review

Abstract

Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease, and also for chronic kidney disease (CKD). A high body mass index is one of the strongest risk factors for new-onset CKD. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing CKD in the long term. The incidence of obesity-related glomerulopathy has increased 10-fold in recent years. Obesity has also been shown to be a risk factor for nephrolithiasis, and for a number of malignancies including kidney cancer. This year the World Kidney Day promotes education on the harmful consequences of obesity and its association with kidney disease, advocating healthy lifestyle and health policy measures that make preventive behaviors an affordable option.

Original languageEnglish (US)
Article number7698
JournalCanadian Journal of Kidney Health and Disease
Volume4
DOIs
StatePublished - 2017

Keywords

  • Chronic kidney disease
  • Kidney cancer
  • Nephrolithiasis
  • Obesity
  • Prevention

ASJC Scopus subject areas

  • Nephrology

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