Obesity and kidney disease: Hidden consequences of the epidemic

Csaba P. Kovesdy, Susan Furth, Carmine Zoccali, Philip Kam Tao Li, Guillermo Garcia-Garcia, Mohammed Benghanem-Gharbi, Rik Bollaert, Sophie Dupuis, Timur Erk, Kamyar Kalantar-Zadeh, Charlotte Osafo, Miguel C. Riella, Elena Zakharova

Research output: Contribution to journalArticlepeer-review

Abstract

Obesity has become a worldwide epidemic, and its prevalence has been projected to grow by 40% in the next decade. This increasing prevalence has implications for the risk of diabetes, cardiovascular disease and also for Chronic Kidney Disease. A high body mass index is one of the strongest risk factors for new-onset Chronic Kidney Disease. In individuals affected by obesity, a compensatory hyperfiltration occurs to meet the heightened metabolic demands of the increased body weight. The increase in intraglomerular pressure can damage the kidneys and raise the risk of developing Chronic Kidney Disease in the long-term. The incidence of obesity-related glomerulopathy has increased ten-fold in recent years. Obesity has also been shown to be a risk factor for nephrolithiasis, and for a number of malignancies including kidney cancer. This year the World Kidney Day promotes education on the harmful consequences of obesity and its association with kidney disease, advocating healthy lifestyle and health policy measures that makes preventive behaviors an affordable option.

Original languageEnglish (US)
Pages (from-to)311-321
Number of pages11
JournalArchivos Espanoles de Urologia
Volume70
Issue number2
StatePublished - Mar 2017

Keywords

  • Chronic kidney disease
  • Kidney cancer
  • Nephrolithiasis
  • Obesity
  • Prevention

ASJC Scopus subject areas

  • Urology

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