Obesity and albuminuria among adults with type 2 diabetes: The look AHEAD (Action for Health in Diabetes) Study

Holly Kramer, David Reboussin, Alain G. Bertoni, Santica Marcovina, Edward Lipkin, Frank L. Greenway, Frederick L. Brancati

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE - To determine the association between obesity measures and albuminuria in adults with type 2 diabetes. RESEARCH DESIGN AND METHODS - In the Look AHEAD (Action for Health in Diabetes) Study, BMI and waist circumference were measured among 4,985 participants while total percent body fat was measured by whole-body DEXA scans among 1,351 participants. Odds of albuminuria by quartiles of BMI, waist circumference, and percent total body fat were calculated using logistic regression analysis while adjusting for covariates. RESULTS - The highest quartile of BMI (odds ratio [OR] 1.72 [95% CI 1.40-2.11]) and waist circumference (OR 1.75 [95% CI 1.42-2.15]) was significantly associated with albuminuria compared with the lowest quartile after adjustment for covariates. No associations were noted between quartiles of percent total body fat and albuminuria in any model. CONCLUSIONS - Increased BMI and abdominal obesity are associated with albuminuria in overweight and obese adults with type 2 diabetes.

Original languageEnglish (US)
Pages (from-to)851-853
Number of pages3
JournalDiabetes care
Volume32
Issue number5
DOIs
StatePublished - May 2009

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

Fingerprint Dive into the research topics of 'Obesity and albuminuria among adults with type 2 diabetes: The look AHEAD (Action for Health in Diabetes) Study'. Together they form a unique fingerprint.

Cite this