Nutritional supplementation during early childhood and bone mineralization during adolescence

Laura Caulfield, J. H. Himes, J. A. Rivera

Research output: Contribution to journalArticle

Abstract

To assess the long-term impact of nutritional supplementation on bone mineralization during adolescence, we studied 356 Guatemalan adolescents who participated from birth to 7 y of age in a controlled supplementation trial. Bone mineralization of the distal radius was assessed using single photon absorptiometry. Children who consumed more cumulative energy from the supplement during childhood had greater bone mineral content, bone width and bone mineral density during adolescence than those who consumed less energy. The associations remained after controlling for each subject's age and gender, and for the type of supplement consumed, but became statistically nonsignificant after adjusting for weight and stature. Because intake of supplement also was associated positively with weight and stature during adolescence, it is concluded that supplementing malnourished children can have a demonstrable long-term impact on bone mineralization, but that the effects are probably not beyond those due to improvements in overall somatic growth associated with supplementation.

Original languageEnglish (US)
JournalJournal of Nutrition
Volume125
Issue number4 SUPPL.
StatePublished - 1995

Fingerprint

adolescence
Physiologic Calcification
bone mineralization
childhood
bones
Bone Density
radius (bone)
energy
bone density
Weights and Measures
mineral content
Photon Absorptiometry
gender
Parturition
Bone and Bones
Growth

Keywords

  • adolescence
  • bone mineralization
  • malnutrition
  • nutritional supplementation

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Nutritional supplementation during early childhood and bone mineralization during adolescence. / Caulfield, Laura; Himes, J. H.; Rivera, J. A.

In: Journal of Nutrition, Vol. 125, No. 4 SUPPL., 1995.

Research output: Contribution to journalArticle

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