NUT Midline Carcinoma of the Nasal Cavity

Mia Edgar, Andria M. Caruso, Esther Kim, Robert D. Foss

Research output: Contribution to journalArticlepeer-review

Abstract

Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, poorly differentiated form of squamous cell carcinoma caused by a chromosomal rearrangement of the NUT gene on chromosome 15. These tumors have a predilection for midline and paramidline structures of the upper aerodigestive tract and mediastinum and can affect patients across a broad age range, including children. In the current example, a 53 year old male presented with a mass originating in the left nasal cavity. The clinical, radiographic, and morphologic features of NMC are discussed.

Original languageEnglish (US)
Pages (from-to)389-392
Number of pages4
JournalHead and Neck Pathology
Volume11
Issue number3
DOIs
StatePublished - Sep 1 2017

Keywords

  • NUT midline carcinoma
  • Nasal
  • Nasal cavity
  • Nuclear protein of testis
  • Radiology
  • Sinonasal
  • Undifferentiated carcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Otorhinolaryngology
  • Oncology

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