Nuclear Medicine Hepatobiliary Imaging

Research output: Contribution to journalArticle

Abstract

Nuclear medicine hepatobilary imaging (HIDA) is a time proven imaging methodology that uses radioactive drugs and specialized cameras to make imaging diagnoses based on physiology. HIDA radiopharmaceuticals are extracted by hepatocytes in the liver and cleared through the biliary system similar to bilirubin. The most common indication for HIDA imaging is acute cholecystitis, diagnosed by nonfilling of the gallbladder due to cystic duct obstruction. HIDA can detect high grade biliary obstruction prior to ductal dilatation; images reveal a persistent hepatogram without biliary clearance due to the high backpressure. HIDA also aids in the diagnosis of partial biliary obstruction due to stones, biliary stricture, and sphincter of Oddi obstruction. It can confirm biliary leakage postcholecystectomy and hepatic transplantation. Calculation of a gallbladder ejection fraction after cholecystokinin infusion is commonly used to diagnose chronic acalculous gallbladder disease. Diseased gallbladders do not contract. There are many other less common but valuable diagnostic indications for HIDA imaging.

Original languageEnglish (US)
Pages (from-to)111-116
Number of pages6
JournalClinical Gastroenterology and Hepatology
Volume8
Issue number2
DOIs
StatePublished - Feb 2010

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Nuclear Medicine
Gallbladder Diseases
Gallbladder
Sphincter of Oddi
Cystic Duct
Acute Cholecystitis
Radiopharmaceuticals
Cholecystokinin
Biliary Tract
Bilirubin
Liver Transplantation
lidofenin
Dilatation
Hepatocytes
Pathologic Constriction
Liver
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Nuclear Medicine Hepatobiliary Imaging. / Ziessman, Harvey.

In: Clinical Gastroenterology and Hepatology, Vol. 8, No. 2, 02.2010, p. 111-116.

Research output: Contribution to journalArticle

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