The normalized velocity of contraction (vn) and its maximal value (vnmax) are related to the normalized flow acceleration within the ventricle, to the subendocardial fiber shortening rate, strain rate, and stress. This paper presents the method of the nuclear medical determination of vn and analyzes a typical volume-velocity-time curve. In 60 patients with different stages of coronary artery disease, global vnmaxshowed good correlation with the minimal ventricular transit time (y=6.18-1.36 x, P<0.001) and global ejection fraction (y=-(2.5+356/(x-104)), P<0.001). The segmental vnmaxshowed a highly significant correlation with the regional ejection fraction (y=-(2.5+371/(x-104)), P<0.001). The mathematical relationships of vn with the mechanical properties of the ventricular wall are described in the appendix.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging