Nuclear magnetic resonance (NMR) imaging in white matter disease of the brain using spin-echo sequences

I. R. Young, C. P. Randeil, Peter W Kaplan, A. James, G. M. Bydder, R. E. Steiner

Research output: Contribution to journalArticle


Attention is drawn to the use of nuclear magnetic resonance (NMR) spin-echo sequences in the recognition of white matter disease of the brain. In 5 patients with multiple sclerosis. 8 lesions were seen with postcontrast x-ray computed tomography (CD (37.5 g of iodine). 33 with inversion-recovery (IR) scans, and 47 with spin-echo (SE) scans. Partial volume effects were less of a diagnostic difficulty with SE scans than with IR scans. Extensive areas of abnormal white matter were seen with CT. IR. and SE scans in a patient with leuco- dystrophy associated with congenital muscular dystrophy. In a patient with ad-renoleucodystrophy focal lesions were seen with CT, IR, and SE scans. In addition, loss of gray-white matter contrast was seen in both occipital lobes with IR scans. Extensive areas of white matter involvement were also seen in a case of Binswangers disease.

Original languageEnglish (US)
Pages (from-to)290-294
Number of pages5
JournalJournal of Computer Assisted Tomography
Issue number2
Publication statusPublished - 1983
Externally publishedYes



  • Brain
  • Nuclear magnetic resonance
  • White-gray matter

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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