Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery

Thomas C. Hutchens, Arash Darafsheh, Amir Fardad, Andrew N. Antoszyk, Howard S. Ying, Vasily N. Astratov, Nathaniel M. Fried

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ophthalmic surgery may benefit from the use of more precise fiber delivery systems for laser surgery. In this study, chains of sapphire microspheres integrated into the distal tip of a hollow waveguide are used for preliminary midinfrared, Erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The combination of the Er:YAG laser's short optical penetration depth and small spot diameters achieved with this novel fiber probe may provide more precise tissue removal. One, three, and five microsphere chain structures were assembled and compared, resulting in spot diameters of 67, 32, and 30 μm, respectively. Single laser pulses of 0.1 mJ energy and 75 μs duration produced craters with average widths of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one, three, and five sphere structures, respectively. Chains of microspheres produced spatial filtering of the multimode Er:YAG laser beam and fiber, thus providing spot diameters not otherwise available for precise tissue ablation using conventional fiber delivery systems. With further probe development, this novel approach to mid-IR laser ablation may provide an alternative to mechanical tools for ultra-precise surgical dissection and removal of ophthalmic tissues.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8218
DOIs
StatePublished - 2012
Externally publishedYes
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XII - San Francisco, CA, United States
Duration: Jan 21 2012Jan 22 2012

Other

OtherOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XII
CountryUnited States
CitySan Francisco, CA
Period1/21/121/22/12

Fingerprint

Laser surgery
Laser Therapy
Microspheres
surgery
infrared lasers
Solid-State Lasers
Tissue
Infrared radiation
YAG lasers
fibers
Fibers
Laser ablation
laser ablation
delivery
Erbium
Dissection
dissection
spatial filtering
Aluminum Oxide
probes

Keywords

  • Erbium
  • Germanium fiber
  • Laser biomedical applications
  • Microsphere
  • Ophthalmic

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Hutchens, T. C., Darafsheh, A., Fardad, A., Antoszyk, A. N., Ying, H. S., Astratov, V. N., & Fried, N. M. (2012). Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8218). [821803] https://doi.org/10.1117/12.905614

Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery. / Hutchens, Thomas C.; Darafsheh, Arash; Fardad, Amir; Antoszyk, Andrew N.; Ying, Howard S.; Astratov, Vasily N.; Fried, Nathaniel M.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8218 2012. 821803.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hutchens, TC, Darafsheh, A, Fardad, A, Antoszyk, AN, Ying, HS, Astratov, VN & Fried, NM 2012, Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8218, 821803, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XII, San Francisco, CA, United States, 1/21/12. https://doi.org/10.1117/12.905614
Hutchens TC, Darafsheh A, Fardad A, Antoszyk AN, Ying HS, Astratov VN et al. Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8218. 2012. 821803 https://doi.org/10.1117/12.905614
Hutchens, Thomas C. ; Darafsheh, Arash ; Fardad, Amir ; Antoszyk, Andrew N. ; Ying, Howard S. ; Astratov, Vasily N. ; Fried, Nathaniel M. / Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8218 2012.
@inproceedings{4757edd25f484d6ebe0236ab61f75a24,
title = "Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery",
abstract = "Ophthalmic surgery may benefit from the use of more precise fiber delivery systems for laser surgery. In this study, chains of sapphire microspheres integrated into the distal tip of a hollow waveguide are used for preliminary midinfrared, Erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The combination of the Er:YAG laser's short optical penetration depth and small spot diameters achieved with this novel fiber probe may provide more precise tissue removal. One, three, and five microsphere chain structures were assembled and compared, resulting in spot diameters of 67, 32, and 30 μm, respectively. Single laser pulses of 0.1 mJ energy and 75 μs duration produced craters with average widths of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one, three, and five sphere structures, respectively. Chains of microspheres produced spatial filtering of the multimode Er:YAG laser beam and fiber, thus providing spot diameters not otherwise available for precise tissue ablation using conventional fiber delivery systems. With further probe development, this novel approach to mid-IR laser ablation may provide an alternative to mechanical tools for ultra-precise surgical dissection and removal of ophthalmic tissues.",
keywords = "Erbium, Germanium fiber, Laser biomedical applications, Microsphere, Ophthalmic",
author = "Hutchens, {Thomas C.} and Arash Darafsheh and Amir Fardad and Antoszyk, {Andrew N.} and Ying, {Howard S.} and Astratov, {Vasily N.} and Fried, {Nathaniel M.}",
year = "2012",
doi = "10.1117/12.905614",
language = "English (US)",
isbn = "9780819488619",
volume = "8218",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Novel microsphere chain fiber tips for use in mid-infrared ophthalmic laser surgery

AU - Hutchens, Thomas C.

AU - Darafsheh, Arash

AU - Fardad, Amir

AU - Antoszyk, Andrew N.

AU - Ying, Howard S.

AU - Astratov, Vasily N.

AU - Fried, Nathaniel M.

PY - 2012

Y1 - 2012

N2 - Ophthalmic surgery may benefit from the use of more precise fiber delivery systems for laser surgery. In this study, chains of sapphire microspheres integrated into the distal tip of a hollow waveguide are used for preliminary midinfrared, Erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The combination of the Er:YAG laser's short optical penetration depth and small spot diameters achieved with this novel fiber probe may provide more precise tissue removal. One, three, and five microsphere chain structures were assembled and compared, resulting in spot diameters of 67, 32, and 30 μm, respectively. Single laser pulses of 0.1 mJ energy and 75 μs duration produced craters with average widths of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one, three, and five sphere structures, respectively. Chains of microspheres produced spatial filtering of the multimode Er:YAG laser beam and fiber, thus providing spot diameters not otherwise available for precise tissue ablation using conventional fiber delivery systems. With further probe development, this novel approach to mid-IR laser ablation may provide an alternative to mechanical tools for ultra-precise surgical dissection and removal of ophthalmic tissues.

AB - Ophthalmic surgery may benefit from the use of more precise fiber delivery systems for laser surgery. In this study, chains of sapphire microspheres integrated into the distal tip of a hollow waveguide are used for preliminary midinfrared, Erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The combination of the Er:YAG laser's short optical penetration depth and small spot diameters achieved with this novel fiber probe may provide more precise tissue removal. One, three, and five microsphere chain structures were assembled and compared, resulting in spot diameters of 67, 32, and 30 μm, respectively. Single laser pulses of 0.1 mJ energy and 75 μs duration produced craters with average widths of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one, three, and five sphere structures, respectively. Chains of microspheres produced spatial filtering of the multimode Er:YAG laser beam and fiber, thus providing spot diameters not otherwise available for precise tissue ablation using conventional fiber delivery systems. With further probe development, this novel approach to mid-IR laser ablation may provide an alternative to mechanical tools for ultra-precise surgical dissection and removal of ophthalmic tissues.

KW - Erbium

KW - Germanium fiber

KW - Laser biomedical applications

KW - Microsphere

KW - Ophthalmic

UR - http://www.scopus.com/inward/record.url?scp=84861984309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861984309&partnerID=8YFLogxK

U2 - 10.1117/12.905614

DO - 10.1117/12.905614

M3 - Conference contribution

SN - 9780819488619

VL - 8218

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -