Novel association of smaller anterior chamber width with angle closure in Singaporeans

Monisha E. Nongpiur, Lisandro M. Sakata, David S Friedman, Mingguang He, Yiong Huak Chan, Raghavan Lavanya, Tien Yin Wong, Tin Aung

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Abstract

Purpose: To describe variations in anterior chamber width (ACW) and investigate its association with the presence of narrow angles. Design: Cross-sectional study. Participants: We recruited 2047 subjects aged 50 years or more from a community polyclinic and 111 subjects with primary angle closure (PAC) or primary angle closure glaucoma (PACG) from an eye hospital in Singapore. Methods: All participants underwent gonioscopy, anterior chamber depth (ACD) and axial length (AL) measurement (IOLMaster; Carl Zeiss, Jena, Germany), and anterior-segment optical coherence tomography (AS-OCT, Visante, Carl Zeiss Meditec, Dublin, CA). Customized software was used to measure the ACW, defined as the distance between the scleral spurs in the horizontal (nasal-temporal) axis of AS-OCT scans. An eye was deemed to have narrow angles if the posterior trabecular meshwork was not visible for at least 180 degrees on non-indentation gonioscopy with the eye in the primary position. Main Outcome Measures: Anterior chamber width and narrow angles. Results: Data on 1465 community-based subjects were available for analysis. Anterior chamber width was significantly smaller in women compared with men (11.70 mm vs. 11.81 mm, respectively, P

Original languageEnglish (US)
Pages (from-to)1967-1973
Number of pages7
JournalOphthalmology
Volume117
Issue number10
DOIs
Publication statusPublished - Oct 2010

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ASJC Scopus subject areas

  • Ophthalmology
  • Medicine(all)

Cite this

Nongpiur, M. E., Sakata, L. M., Friedman, D. S., He, M., Chan, Y. H., Lavanya, R., ... Aung, T. (2010). Novel association of smaller anterior chamber width with angle closure in Singaporeans. Ophthalmology, 117(10), 1967-1973. https://doi.org/10.1016/j.ophtha.2010.02.007