TY - JOUR
T1 - Novel and effective disposable device that provides 2-way protection to the duodenoscope from microbial contamination
AU - Pasricha, Pankaj J.
AU - Miller, Scott
AU - Carter, Frank
AU - Humphries, Romney
N1 - Funding Information:
DISCLOSURE: The following authors disclosed financial relationships: P. J. Pasricha: Consultant for GI Scientific LLC, Pentax, and Olympus; equity holder in GI Scientific LLC. S. Miller: Chief Executive Officer for GI Scientific LLC. F. Carter: Chief Operating Officer for GI Scientific LLC. R. Humphries: Consultant for GI Scientific LLC and Qpex Pharmaceuticals; he is employed by and is a shareholder for Accelerate Diagnostics Research support for this study was provided by GI Scientific LLC.
Publisher Copyright:
© 2020 American Society for Gastrointestinal Endoscopy
PY - 2020/7
Y1 - 2020/7
N2 - Background and Aims: Duodenoscope contamination is associated with notable patient morbidity and mortality and can occur despite high-level disinfection protocols, requiring a solution that protects against contamination of the endoscope in the first place. Methods: We assessed a newly cleared, single-use device to seal the distal end of duodenoscopes while preserving optics and other endoscope functionality and tested its ability to protect against contamination using dye immersion tests and microbial inoculation. Results: Dye immersion tests revealed a complete seal with no leakage. Rigorous microbial challenge tests showed the device can both protect against contamination of the endoscope by external microbes (“outside-in” protection) and shield instruments from contact with pre-existing microbial biofilm on or around the elevator that may have survived reprocessing (“inside-out” protection). Optical and mechanical performance of the endoscope was not compromised by the addition of the device. Conclusions: The results show that this disposable device provides 2-way protection to the duodenoscope from microbial contamination, without the potential for disrupting current equipment, technique, and workflow.
AB - Background and Aims: Duodenoscope contamination is associated with notable patient morbidity and mortality and can occur despite high-level disinfection protocols, requiring a solution that protects against contamination of the endoscope in the first place. Methods: We assessed a newly cleared, single-use device to seal the distal end of duodenoscopes while preserving optics and other endoscope functionality and tested its ability to protect against contamination using dye immersion tests and microbial inoculation. Results: Dye immersion tests revealed a complete seal with no leakage. Rigorous microbial challenge tests showed the device can both protect against contamination of the endoscope by external microbes (“outside-in” protection) and shield instruments from contact with pre-existing microbial biofilm on or around the elevator that may have survived reprocessing (“inside-out” protection). Optical and mechanical performance of the endoscope was not compromised by the addition of the device. Conclusions: The results show that this disposable device provides 2-way protection to the duodenoscope from microbial contamination, without the potential for disrupting current equipment, technique, and workflow.
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U2 - 10.1016/j.gie.2020.03.001
DO - 10.1016/j.gie.2020.03.001
M3 - Article
C2 - 32151661
AN - SCOPUS:85084831456
SN - 0016-5107
VL - 92
SP - 199
EP - 208
JO - Gastrointestinal endoscopy
JF - Gastrointestinal endoscopy
IS - 1
ER -