Nosocomial transmission of tuberculosis among mentally-handicapped patients in a long-term care facility

N. Lemaître, W. Sougakoff, D. Coëtmeur, J. Vaucel, V. Jarlier, J. Grosset

Research output: Contribution to journalArticle

Abstract

Setting: A long-term care facility at Saint-Brieuc hospital, France. Objective: To investigate a nosocomial outbreak of culture-positive pulmonary tuberculosis in 6 (40%) of 15 mentally handicapped HIV-seronegative patients. Design: The factors contributing to the outbreak were analyzed and the restriction fragment length polymorphism (RFLP) patterns of the six Mycobacterium tuberculosis strains were compared. Results: RFLP analysis of the six strains demonstrated an identical banding pattern, thus confirming the spread of a unique strain. A prolonged period of contagiousness due to a delay in diagnosis of the source patient, as well as crowded living conditions in the facility, probably contributed to the outbreak. Surveillance of residents and staff in contact with the source patient resulted in the detection of five secondary cases. Because effective isolation of mentally handicapped patients in the long-term care facility turned out to be difficult, the six case-patients were transferred to the pneumology department, thus limiting the spread of tuberculosis to other residents and staff. Conclusions: The present outbreak emphasizes the difficulties of implementing control measures for preventing the nosocomial transmission of tuberculosis in long-term care facilities for mentally handicapped patients.

Original languageEnglish (US)
Pages (from-to)531-536
Number of pages6
JournalTubercle and Lung Disease
Volume77
Issue number6
DOIs
StatePublished - 1996
Externally publishedYes

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Mentally Disabled Persons
Long-Term Care
Tuberculosis
Disease Outbreaks
Restriction Fragment Length Polymorphisms
Pulmonary Medicine
Saints
Social Conditions
Pulmonary Tuberculosis
Mycobacterium tuberculosis
France
HIV

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Immunology
  • Microbiology

Cite this

Nosocomial transmission of tuberculosis among mentally-handicapped patients in a long-term care facility. / Lemaître, N.; Sougakoff, W.; Coëtmeur, D.; Vaucel, J.; Jarlier, V.; Grosset, J.

In: Tubercle and Lung Disease, Vol. 77, No. 6, 1996, p. 531-536.

Research output: Contribution to journalArticle

Lemaître, N, Sougakoff, W, Coëtmeur, D, Vaucel, J, Jarlier, V & Grosset, J 1996, 'Nosocomial transmission of tuberculosis among mentally-handicapped patients in a long-term care facility', Tubercle and Lung Disease, vol. 77, no. 6, pp. 531-536. https://doi.org/10.1016/S0962-8479(96)90051-9
Lemaître, N. ; Sougakoff, W. ; Coëtmeur, D. ; Vaucel, J. ; Jarlier, V. ; Grosset, J. / Nosocomial transmission of tuberculosis among mentally-handicapped patients in a long-term care facility. In: Tubercle and Lung Disease. 1996 ; Vol. 77, No. 6. pp. 531-536.
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AU - Jarlier, V.

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