Normalisation of histogrammed list mode data

Kris Thielemans, Christian Morel, Matthew W. Jacobson, Jerome H. Kaempf, Sanida Mustafovic

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Many PET scanners nowadays have the possibility to record event-by-event information, known as list mode data. This has the advantage of keeping the data in the highest possible resolution (both temporal and spatial). In most cases, list mode data are then binned into sinogram format before reconstruction. In this paper, we discuss at which stage normalisation factors should be introduced. It is shown that noise is greatly reduced by performing the normalisation after the binning. We illustrate this with acquired and simulated data for the quad HiDAC camera.

Original languageEnglish (US)
Pages (from-to)543-551
Number of pages9
JournalIEEE Transactions on Nuclear Science
Issue number1
StatePublished - Feb 2008
Externally publishedYes


  • Data normalisation
  • List mode
  • PET

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering
  • Electrical and Electronic Engineering


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