Normal Human Right and Left Ventricular Mass, Systolic Function, and Gender Differences by Cine Magnetic Resonance Imaging

Christine H. Lorenz, Eloisa S. Walker, Victoria L. Morgan, Stacy S. Klein, Thomas P. Graham

Research output: Contribution to journalArticle

Abstract

Our objective was to establish normal ranges of left and right ventricular mass and function with cine magnetic resonance imaging (MRI) and to determine gender differences. Seventy-five healthy subjects (age range 8-55, mean 28 yr) were studied with cine MRI. Ten dogs were imaged for autopsy validation with a mean difference between actual and MRI-determined mass of 0.2 A ± 8.4 g. Intraobserver and interobserver variability and interstudy variability were 5-6%. All parameters were significantly different between males and females except ejection fraction and the left ventricular mass to end-diastolic volume ratio. Agreement with published autopsy series, including gender differences, was excellent. This study presents normative MRI data that can be used for comparing individual patients and for further study of right and left ventricular interaction.

Original languageEnglish (US)
Pages (from-to)7-21
Number of pages15
JournalJournal of Cardiovascular Magnetic Resonance
Volume1
Issue number1
StatePublished - 1999
Externally publishedYes

Keywords

  • Left ventricle
  • Magnetic resonance imaging
  • Normative values
  • Right ventricle
  • Ventricular function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Family Practice

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