Noradrenergic systems in human cerebellum

Richard E. Powers; Daniel T. O'Connor; Donald L. Price

doi:10.1016/0006-8993(89)90504-0

Noradrenergic systems in human cerebellum

Richard E. Powers, Daniel T. O'Connor, Donald L. Price

School of Medicine

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Thin, beaded axons, immunostained with antisera to human β-hydroxylase (DBH), were present in all layers of the anterior vermis of human cerebellum. This plexus appears similar to that described in rodents and provides information complementary to receptor autoradiographic studies that show significant noradrenergic innervation of mammalian cerebellum. Moreover, in two aged controls, we demonstrated abnormal, swollen, tortuous axons not visualized in young controls.

Original language	English (US)
Pages (from-to)	194-199
Number of pages	6
Journal	Brain research
Volume	481
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(89)90504-0
State	Published - Feb 27 1989

Keywords

Abnormal axon
Norepinephrine

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(89)90504-0

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title = "Noradrenergic systems in human cerebellum",

abstract = "Thin, beaded axons, immunostained with antisera to human β-hydroxylase (DBH), were present in all layers of the anterior vermis of human cerebellum. This plexus appears similar to that described in rodents and provides information complementary to receptor autoradiographic studies that show significant noradrenergic innervation of mammalian cerebellum. Moreover, in two aged controls, we demonstrated abnormal, swollen, tortuous axons not visualized in young controls.",

keywords = "Abnormal axon, Norepinephrine",

author = "Powers, {Richard E.} and O'Connor, {Daniel T.} and Price, {Donald L.}",

note = "Funding Information: The authorst hank James J. Geyer for excellent technical assistanceT. his work was supportedb y grantsf rom the U.S. Public HealthS ervice( NIH NS 07179,A G 05146,A G 03359,H L 25457)a nd funds",

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doi = "10.1016/0006-8993(89)90504-0",

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T1 - Noradrenergic systems in human cerebellum

AU - Powers, Richard E.

AU - O'Connor, Daniel T.

AU - Price, Donald L.

N1 - Funding Information: The authorst hank James J. Geyer for excellent technical assistanceT. his work was supportedb y grantsf rom the U.S. Public HealthS ervice( NIH NS 07179,A G 05146,A G 03359,H L 25457)a nd funds

PY - 1989/2/27

Y1 - 1989/2/27

N2 - Thin, beaded axons, immunostained with antisera to human β-hydroxylase (DBH), were present in all layers of the anterior vermis of human cerebellum. This plexus appears similar to that described in rodents and provides information complementary to receptor autoradiographic studies that show significant noradrenergic innervation of mammalian cerebellum. Moreover, in two aged controls, we demonstrated abnormal, swollen, tortuous axons not visualized in young controls.

AB - Thin, beaded axons, immunostained with antisera to human β-hydroxylase (DBH), were present in all layers of the anterior vermis of human cerebellum. This plexus appears similar to that described in rodents and provides information complementary to receptor autoradiographic studies that show significant noradrenergic innervation of mammalian cerebellum. Moreover, in two aged controls, we demonstrated abnormal, swollen, tortuous axons not visualized in young controls.

KW - Abnormal axon

KW - Norepinephrine

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JO - Brain Research

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Noradrenergic systems in human cerebellum

Abstract

Keywords

ASJC Scopus subject areas

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