Noradrenergic innervation of human inferior olivary complex

Richard E. Powers; Daniel T. O'Connor; Donald L. Price

doi:10.1016/0006-8993(90)91650-6

Noradrenergic innervation of human inferior olivary complex

Richard E. Powers, Daniel T. O'Connor, Donald L. Price

School of Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Antisera to human dopamine β-hydroxylase (DBH) was used to stain noradrenergic axons in the inferior olivary complex (IOC) of human controls. A modest plexus of thin, beaded, immunoreactive fibers was present in all subdivisions of the IOC, and many fibers coursed in the rostrocaudal axis. This noradrenergic plexus is similar to that of monkey, provides complementary evidence to reports of β-adrenergic receptors in human IOC, and supports the concept of noradrenergic projections to IOC.

Original language	English (US)
Pages (from-to)	151-155
Number of pages	5
Journal	Brain research
Volume	523
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(90)91650-6
State	Published - Jul 16 1990

Keywords

Dopamine β-hydroxylase
Immunocytochemistry

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(90)91650-6

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title = "Noradrenergic innervation of human inferior olivary complex",

abstract = "Antisera to human dopamine β-hydroxylase (DBH) was used to stain noradrenergic axons in the inferior olivary complex (IOC) of human controls. A modest plexus of thin, beaded, immunoreactive fibers was present in all subdivisions of the IOC, and many fibers coursed in the rostrocaudal axis. This noradrenergic plexus is similar to that of monkey, provides complementary evidence to reports of β-adrenergic receptors in human IOC, and supports the concept of noradrenergic projections to IOC.",

keywords = "Dopamine β-hydroxylase, Immunocytochemistry",

author = "Powers, {Richard E.} and O'Connor, {Daniel T.} and Price, {Donald L.}",

note = "Funding Information: This work was supported by grants from the U.S. Public Health Service (NIH AG 05146, AG 03359, HL 25457) and funds from Point of View Inc. D.L.P. is the recipient of a Javits Neuroscience Investigator Award (NIH NS 10580) and a Leadership and Excellence in Alzheimer's Disease (LEAD) award (NIA AG 07914).",

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doi = "10.1016/0006-8993(90)91650-6",

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T1 - Noradrenergic innervation of human inferior olivary complex

AU - Powers, Richard E.

AU - O'Connor, Daniel T.

AU - Price, Donald L.

N1 - Funding Information: This work was supported by grants from the U.S. Public Health Service (NIH AG 05146, AG 03359, HL 25457) and funds from Point of View Inc. D.L.P. is the recipient of a Javits Neuroscience Investigator Award (NIH NS 10580) and a Leadership and Excellence in Alzheimer's Disease (LEAD) award (NIA AG 07914).

PY - 1990/7/16

Y1 - 1990/7/16

N2 - Antisera to human dopamine β-hydroxylase (DBH) was used to stain noradrenergic axons in the inferior olivary complex (IOC) of human controls. A modest plexus of thin, beaded, immunoreactive fibers was present in all subdivisions of the IOC, and many fibers coursed in the rostrocaudal axis. This noradrenergic plexus is similar to that of monkey, provides complementary evidence to reports of β-adrenergic receptors in human IOC, and supports the concept of noradrenergic projections to IOC.

AB - Antisera to human dopamine β-hydroxylase (DBH) was used to stain noradrenergic axons in the inferior olivary complex (IOC) of human controls. A modest plexus of thin, beaded, immunoreactive fibers was present in all subdivisions of the IOC, and many fibers coursed in the rostrocaudal axis. This noradrenergic plexus is similar to that of monkey, provides complementary evidence to reports of β-adrenergic receptors in human IOC, and supports the concept of noradrenergic projections to IOC.

KW - Dopamine β-hydroxylase

KW - Immunocytochemistry

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SP - 151

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JO - Brain research

JF - Brain research

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ER -

Noradrenergic innervation of human inferior olivary complex

Abstract

Keywords

ASJC Scopus subject areas

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