Nonneoplastic Neuroma After Radical Prostatectomy Is Not a Mimicker of Lymph Node Metastases on 68Ga–PSMA Ligand PET/CT

Thorsten Derlin, Udo Schumacher, Frank M. Bengel

Research output: Contribution to journalArticle


ABSTRACT: Traumatic neuroma is frequently observed after surgery. PSMA expression has been demonstrated in neoplastic nerve sheath tumors, which may mimic metastases on PSMA imaging. In this case, histopathologic evaluation of a pelvic lesion with assumed intense tracer uptake on Ga-PSMA ligand PET/CT in a patient with biochemical recurrence of prostate cancer revealed an amputation neuroma. However, immunohistochemical evaluation showed absent PSMA expression, and follow-up PET confirmed persistence of the metastasis. Unlike neoplastic nerve sheath tumors, traumatic neuroma does not show PSMA expression and is not a mimicker of metastases on Ga-PSMA PET/CT.

Original languageEnglish (US)
JournalClinical Nuclear Medicine
StateAccepted/In press - Aug 24 2016
Externally publishedYes


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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