Noninfectious Complications of Transfusion: Adverse Events

Sara Rutter, Christopher A. Tormey, Amit Gokhale

Research output: Chapter in Book/Report/Conference proceedingChapter


Despite the significant strides that have been made to improve the safety of blood product transfusion over the past several decades, there still remain potential risks to the administration of these components. With such adverse events, also termed transfusion reactions, disorders can range from severe and life-threatening to transient and mild. Due to the wide spectrum of disorders that can be associated with transfusion, and the need to intervene to prevent poor outcomes, it is vital that practicing clinical pathologists, blood bankers, and those engaged in the field of hematology have a detailed working knowledge of how to recognize and classify transfusion-associated adverse events. As such, the aims of this chapter are (1) to introduce readers to each of the various common and less frequent types of transfusion reactions, (2) to review the incidence and basic pathophysiology of these adverse events, and (3) to discuss practical approaches to treat and prevent these disorders. We also seek to provide a basic framework on the approach to evaluating transfusion reactions from a general perspective.

Original languageEnglish (US)
Title of host publicationClinical Principles of Transfusion Medicine
Number of pages16
ISBN (Electronic)9780323544597
ISBN (Print)9780323544580
StatePublished - Feb 1 2018
Externally publishedYes


  • Allergic reactions
  • Febrile reactions
  • Hemolytic transfusion reactions
  • Septic transfusion reactions
  • TACO
  • Transfusion adverse events
  • Transfusion reactions

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Noninfectious Complications of Transfusion: Adverse Events'. Together they form a unique fingerprint.

Cite this