Non-trigger anesthesia management in a patient with Leigh’s syndrome presenting for dental rehabilitation

M-Irfan Suleman, Thejovathi Edala, Edwin Abraham, M. Saif Siddiqu

Research output: Contribution to journalArticle


Introduction: Usually presenting in infancy, Leigh’s syndrome is an inherited condition often manifesting with seizures, ataxia, developmental delay, and dysarthria. The disorder is rare, appearing in approximately 1 in 40,000 live births. Consequently, providing these patients with a suitable plan by which to administer anesthetics remains problematic. Case Presentation: We report a male patient with Leigh’s syndrome and a family history suggestive of unknown hypotonia and malignant hyperthermia presenting for dental rehabilitation. Conclusions: Dexmedetomidine with remifentanil can be used with no complication in this senerio.

Original languageEnglish (US)
Article numbere28804
JournalAnesthesiology and Pain Medicine
Issue number6
Publication statusPublished - Dec 1 2015
Externally publishedYes



  • Anesthesia
  • Encephalomyelopathy
  • Leigh’s syndrome
  • Malignant hyperthermia
  • Mitochondrial disorders

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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