Abstract
Recurrent event data are commonly encountered in health-related longitudinal studies. In this paper time-to-events models for recurrent event data are studied with non-informative and informative censorings. In statistical literature, the risk set methods have been confirmed to serve as an appropriate and efficient approach for analysing recurrent event data when censoring is non-informative. This approach produces biased results, however, when censoring is informative for the time-to-events outcome data. We compare the risk set methods with alternative non-parametric approaches which are robust subject to informative censoring. In particular, non-parametric procedures for the estimation of the cumulative occurrence rate function (CORF) and the occurrence rate function (ORF) are discussed in detail. Simulation and an analysis of data from the AIDS Link to Intravenous Experiences Cohort Study is presented.
Original language | English (US) |
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Pages (from-to) | 445-456 |
Number of pages | 12 |
Journal | Statistics in Medicine |
Volume | 21 |
Issue number | 3 |
DOIs | |
State | Published - Feb 15 2002 |
Keywords
- Cumulative rate function
- Informative censoring
- Intensity function
- Kernal estimation
- Rate function
- Recurrent events
ASJC Scopus subject areas
- Epidemiology
- Statistics and Probability