Non-operative management of rectal cancer

Jonathan Greer, Alexander T. Hawkins

Research output: Contribution to journalArticle

Abstract

Despite advances in technique, surgical resection of rectal cancer remains a morbid procedure that can lead to a profound decrease in a patient's quality of life. A novel method of management, termed “Non-operative management” (NOM), mirrors the management of anal carcinoma. Patients undergo definitive treatment with only chemotherapy and radiation, with resection reserved only for salvage. Current data is encouraging- both in reduction in morbidity and similar, if not superior oncologic results. However, there are a number of barriers to the wide adoption of this practice. This manuscript seeks to describe the rationale and execution of NOM as well as present the current data and pitfalls of the approach.

Original languageEnglish (US)
Pages (from-to)79-84
Number of pages6
JournalSeminars in Colon and Rectal Surgery
Volume30
Issue number2
DOIs
StatePublished - Jun 1 2019

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Rectal Neoplasms
Quality of Life
Radiation
Morbidity
Carcinoma
Drug Therapy
Therapeutics

Keywords

  • Chemotherapy
  • Radiotherapy
  • Rectal cancer
  • “Non-operative management”
  • “Watch and wait”

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Non-operative management of rectal cancer. / Greer, Jonathan; Hawkins, Alexander T.

In: Seminars in Colon and Rectal Surgery, Vol. 30, No. 2, 01.06.2019, p. 79-84.

Research output: Contribution to journalArticle

Greer, Jonathan ; Hawkins, Alexander T. / Non-operative management of rectal cancer. In: Seminars in Colon and Rectal Surgery. 2019 ; Vol. 30, No. 2. pp. 79-84.
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