Non-Mendelian inheritance of mosquito susceptibility to infection with Brugia malayi and Brugia pahangi

Milan Trpis, Richard E. Duhrkopf, Karen L. Parker

Research output: Contribution to journalArticlepeer-review

Abstract

The mode of inheritance of susceptibility or refractoriness of insect vectors to medically important pathogens such as those causing malaria or filariasis is usually believed to follow normal Mendelian laws and to involve a single pair of alleles. In this report, experiments are described that demonstrate another mode of inheritance of mosquito susceptibility to filarial parasites. Crosses were made between susceptible and refractory species of the Aedes scutellaris complex, and the hybrid and backcross progeny were tested for susceptibility to infection by Brugia malayi and Brugia pahangi. The data indicate that inheritance follows a non-Mendelian pattern indicative of extrachromosomal factors inherited through the maternal parent.

Original languageEnglish (US)
Pages (from-to)1435-1437
Number of pages3
JournalScience
Volume212
Issue number4489
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • General

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