Non-human primate regulatory T cells: Current biology and implications for transplantation

Eefje M. Dons, Giorgio Raimondi, David K.C. Cooper, Angus W. Thomson

Research output: Contribution to journalArticle

Abstract

Regulatory T cells (Treg) offer potential for improving long-term outcomes in cell and organ transplantation. The non-human primate model is a valuable resource for addressing issues concerning the transfer of Treg therapy to the clinic. Herein, we discuss the properties of non-human primate Treg and prospects for their evaluation in allotransplantation and xenotransplantation.

Original languageEnglish (US)
Pages (from-to)811-816
Number of pages6
JournalTransplantation
Volume90
Issue number8
DOIs
StatePublished - Oct 27 2010
Externally publishedYes

Keywords

  • Non-human primates
  • Regulatory T cells
  • Transplantation
  • Xenotransplantation

ASJC Scopus subject areas

  • Transplantation

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