Abstract
Non-Hodgkin lymphoma (NHL) refers to a group of diverse tumors derived from cells of lymphocytic lineage. They occur as clonal proliferations of single cells at any stage of lymphocyte development. In contrast to adult NHL, childhood NHL are typically high grade, tend to present as advanced disease, yet with intensive multiagent chemotherapy, the outcome is favorable. Active research is aimed at minimizing late effects in childhood cancer survivors, studying biological differences, and identifying high-risk populations who may benefit from novel targeted therapies.
Original language | English (US) |
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Title of host publication | Neoplastic Diseases of the Blood |
Publisher | Springer New York |
Pages | 1049-1072 |
Number of pages | 24 |
ISBN (Electronic) | 9781461437642 |
ISBN (Print) | 1461437636, 9781461437635 |
DOIs | |
State | Published - Nov 1 2013 |
Externally published | Yes |
Keywords
- Bone marrow biopsy
- Chemotherapy
- Combination chemotherapy
- Lymph node biopsy
- Monoclonal antibody therapy
ASJC Scopus subject areas
- General Medicine