Noise reduction in 3D perfusion imaging by attenuating the static signal in arterial spin tagging (ASSIST)

Frank Q. Ye, Joseph A. Frank, Daniel R. Weinberger, Alan C. McLaughlin

Research output: Contribution to journalArticlepeer-review

Abstract

Phase-encoded multishot SPIRAL approaches were used to acquire true 3D cerebral blood flow images of the human head using arterial spin tagging approaches. Multiple-inversion background suppression techniques, which suppress phase noise due to interacquisition fluctuations in the static magnetic field, reduced the temporal standard deviation of true 3D ΔM images acquired using arterial spin tagging approaches by ~50%. Background suppressed arterial spin tagging (ASSIST) approaches were used to obtain high-resolution isotropic true 3D cerebral blood flow images, and to obtain true 3D activation images during cognitive (working memory) tasks.

Original languageEnglish (US)
Pages (from-to)92-100
Number of pages9
JournalMagnetic resonance in medicine
Volume44
Issue number1
DOIs
StatePublished - 2000
Externally publishedYes

Keywords

  • Arterial spin tagging
  • Background suppression
  • Cerebral blood flow
  • Human, brain

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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