No decrease in clindamycin susceptibility despite increased use of clindamycin for pediatric community-associated methicillin-resistant Staphylococcus aureus skin infections

Jillian M. Szczesiul, Kenneth M. Shermock, Umbreen Idrees Murtaza, George K. Siberry

Research output: Contribution to journalArticlepeer-review

Abstract

A previous study at our institution revealed 98% of methicillin-resistant Staphylococcus aureus (MRSA) isolates were susceptible to clindamycin; however, β-lactams were then the predominant empiric treatment. This follow-up chart review study examined subsequent staphylococcal skin and soft tissue infection treatment and susceptibility patterns over a 2-year period. Of 296 S. aureus skin and soft tissue infections, 73% were MRSA, of which 87% were community-associated-MRSA; MRSA infections peaked in warm summer months. Despite a significant increase in empiric clindamycin use, 97% of community-associated- MRSA isolates retained susceptibility to clindamycin.

Original languageEnglish (US)
Pages (from-to)852-854
Number of pages3
JournalPediatric Infectious Disease Journal
Volume26
Issue number9
DOIs
StatePublished - Sep 2007

Keywords

  • CA-MRSA
  • Clindamycin
  • MRSA
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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