No amikacin, no problem: A Successful Treatment Approach for Pediatric Otomastoiditis Due to Amikacin-Resistant Mycobacterium abscessus

William J. Richter, Keira A. Cohen

Research output: Contribution to journalReview article

Abstract

Pediatric otomastoiditis due to Mycobacterium abscessus can be a devastating infection that presents multiple treatment challenges. Van Wijk et al. report the use of a structured approach with a standardized regimen of intravenous (i.v.), topical, and oral antibiotics and surgical intervention for four pediatric patients with multidrug-resistant Mycobacterium abscessus otomastoiditis. Despite treatment-related adverse events, all four patients achieved sustained cure with this approach. This case series provides a framework for managing drug-resistant Mycobacterium abscessus otomastoiditis.

Original languageEnglish (US)
Article numbere02023-19
JournalAntimicrobial agents and chemotherapy
Volume64
Issue number1
DOIs
StatePublished - 2020

Keywords

  • Mycobacterium abscessus
  • Pediatric otomastoiditis

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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