NMR studies of brain 13C-glucose uptake and metabolism: Present status

Peter C Van Zijl, Doug Rothman

Research output: Contribution to journalArticle

Abstract

One of the common features of epilepsy is a change in glucose metabolism at the site of seizure activity during and between seizures. The noninvasive in situ study of glucose transport and metabolism by NMR can potentially provide detailed information about this phenomena. In this short review, we will discuss the principles of 13C-glucose NMR studies of the brain and compare the advantages and disadvantages of this method to those of 18F-deoxyglucose studies using positron emission tomography (PET).

Original languageEnglish (US)
Pages (from-to)1213-1221
Number of pages9
JournalMagnetic Resonance Imaging
Volume13
Issue number8
DOIs
StatePublished - 1995

Fingerprint

metabolism
Metabolism
glucose
seizures
brain
Glucose
Brain
Nuclear magnetic resonance
nuclear magnetic resonance
Seizures
epilepsy
Positron emission tomography
Deoxyglucose
Positron-Emission Tomography
Epilepsy
positrons
tomography

Keywords

  • Brain
  • Glucose metabolism
  • Glucose transport
  • Magnetic resonance

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Clinical Biochemistry
  • Structural Biology
  • Condensed Matter Physics

Cite this

NMR studies of brain 13C-glucose uptake and metabolism : Present status. / Van Zijl, Peter C; Rothman, Doug.

In: Magnetic Resonance Imaging, Vol. 13, No. 8, 1995, p. 1213-1221.

Research output: Contribution to journalArticle

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