Abstract
Some individuals maintain high cognitive functioning at older ages. Here we show that mechanisms for long-term depression differ in aged rodents that maintain cognitive performance compared to young adults. Our results imply that cognitive abilities may be sustained in aged individuals by a switch in synaptic plasticity mechanisms.
Original language | English (US) |
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Pages (from-to) | 1657-1659 |
Number of pages | 3 |
Journal | Nature neuroscience |
Volume | 8 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2005 |
ASJC Scopus subject areas
- Neuroscience(all)