Nitrous Oxide and Fertility

Ronald H. Gray; Andrew S. Rowland; Donna Day Baird; Clarice R. Weinberg; Jay B. Brodsky; Patricia A. Baird

doi:10.1056/NEJM199301283280414

Nitrous Oxide and Fertility

Ronald H. Gray, Andrew S. Rowland, Donna Day Baird, Clarice R. Weinberg, Jay B. Brodsky, Patricia A. Baird

Bloomberg School of Public Health

Research output: Contribution to journal › Letter › peer-review

4 Scopus citations

Abstract

To the Editor: The study by Rowland et al. (Oct. 1 issue)¹ clearly demonstrated reduced fertility among female dental assistants exposed to high levels of unscavenged nitrous oxide. The authors also reported, but did not comment on, a higher rate of spontaneous abortion (50 percent) in 10 pregnant women exposed to high levels of unscavenged nitrous oxide, as compared with an 8 percent rate of fetal loss in 315 pregnant women with no exposure to nitrous oxide or exposure to a lower level. This difference is significant (P = 0.001 by Fisher's exact test) and suggests that nitrous oxide may…

Original language	English (US)
Pages (from-to)	284-285
Number of pages	2
Journal	New England Journal of Medicine
Volume	328
Issue number	4
DOIs	https://doi.org/10.1056/NEJM199301283280414
State	Published - Jan 28 1993

ASJC Scopus subject areas

General Medicine

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title = "Nitrous Oxide and Fertility",

abstract = "To the Editor: The study by Rowland et al. (Oct. 1 issue)1 clearly demonstrated reduced fertility among female dental assistants exposed to high levels of unscavenged nitrous oxide. The authors also reported, but did not comment on, a higher rate of spontaneous abortion (50 percent) in 10 pregnant women exposed to high levels of unscavenged nitrous oxide, as compared with an 8 percent rate of fetal loss in 315 pregnant women with no exposure to nitrous oxide or exposure to a lower level. This difference is significant (P = 0.001 by Fisher's exact test) and suggests that nitrous oxide may…",

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AU - Gray, Ronald H.

AU - Rowland, Andrew S.

AU - Baird, Donna Day

AU - Weinberg, Clarice R.

AU - Brodsky, Jay B.

AU - Baird, Patricia A.

PY - 1993/1/28

Y1 - 1993/1/28

N2 - To the Editor: The study by Rowland et al. (Oct. 1 issue)1 clearly demonstrated reduced fertility among female dental assistants exposed to high levels of unscavenged nitrous oxide. The authors also reported, but did not comment on, a higher rate of spontaneous abortion (50 percent) in 10 pregnant women exposed to high levels of unscavenged nitrous oxide, as compared with an 8 percent rate of fetal loss in 315 pregnant women with no exposure to nitrous oxide or exposure to a lower level. This difference is significant (P = 0.001 by Fisher's exact test) and suggests that nitrous oxide may…

AB - To the Editor: The study by Rowland et al. (Oct. 1 issue)1 clearly demonstrated reduced fertility among female dental assistants exposed to high levels of unscavenged nitrous oxide. The authors also reported, but did not comment on, a higher rate of spontaneous abortion (50 percent) in 10 pregnant women exposed to high levels of unscavenged nitrous oxide, as compared with an 8 percent rate of fetal loss in 315 pregnant women with no exposure to nitrous oxide or exposure to a lower level. This difference is significant (P = 0.001 by Fisher's exact test) and suggests that nitrous oxide may…

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Nitrous Oxide and Fertility

Abstract

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