Nitroimidazoles X . Syntheses of substituted 2‐(1‐methyl‐5‐nitro‐2‐imidazolyl)quinolines

A. Shafiee, K. Parang, M. Khazan, F. Ghasemian

Research output: Contribution to journalArticlepeer-review

Abstract

Reduction of substituted‐2‐nitrobenzaldehyde 1 afforded substituted‐2‐aminobenzaldehyde 2. Reaction of compound 2 with 2‐acetyl‐1‐methyl‐5‐nitroimidazole 3 under basic conditions afforded substituted 2‐(1‐methyl‐5‐nitro‐2‐imidazolyl)quinolines 4. Reaction of compound 4 (R = X) with hydrogen peroxide in acetic acid afforded compound 5 which was transformed to compound 6 with phosphorus oxychloride.

Original languageEnglish (US)
Pages (from-to)1859-1861
Number of pages3
JournalJournal of Heterocyclic Chemistry
Volume29
Issue number7
DOIs
StatePublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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