Nitro-PDI incites toxic waste accumulation

Mark P. Mattson

Research output: Contribution to journalArticlepeer-review

Abstract

In Parkinson disease and related disorders, nitric oxide may disable PDI, an enzyme critical for proper protein folding in the endoplasmic reticulum, resulting in the accumulation of damaged proteins and eventually neuronal death.

Original languageEnglish (US)
Pages (from-to)865-867
Number of pages3
JournalNature Neuroscience
Volume9
Issue number7
DOIs
StatePublished - Jul 2006
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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