Nitric oxide and neurons

Research output: Contribution to journalArticle

Abstract

In the past 2 years powerful evidence has emerged to suggest that nitric oxide functions as a neurotransmitter in both the central and peripheral nervous systems. Recent evidence suggests that it may play a role in mediating forms of synaptic plasticity such as long-term potentiation in the CA1 region of the hippocampus, and long-term depression in the cerebellum. Abnormal secretion of nitric oxide may be responsible for the neurotoxicity mediated by NMDA receptors that results in the pathophysiology of strokes and neurodegenerative diseases.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalCurrent Opinion in Neurobiology
Volume2
Issue number3
DOIs
StatePublished - 1992

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Nitric Oxide
Neurons
Neuronal Plasticity
Long-Term Potentiation
Peripheral Nervous System
N-Methyl-D-Aspartate Receptors
Neurodegenerative Diseases
Cerebellum
Neurotransmitter Agents
Hippocampus
Central Nervous System
Stroke

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Nitric oxide and neurons. / Snyder, Solomon H.

In: Current Opinion in Neurobiology, Vol. 2, No. 3, 1992, p. 323-327.

Research output: Contribution to journalArticle

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