Nitric oxide and neurons

Research output: Contribution to journalArticlepeer-review


In the past 2 years powerful evidence has emerged to suggest that nitric oxide functions as a neurotransmitter in both the central and peripheral nervous systems. Recent evidence suggests that it may play a role in mediating forms of synaptic plasticity such as long-term potentiation in the CA1 region of the hippocampus, and long-term depression in the cerebellum. Abnormal secretion of nitric oxide may be responsible for the neurotoxicity mediated by NMDA receptors that results in the pathophysiology of strokes and neurodegenerative diseases.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalCurrent Opinion in Neurobiology
Issue number3
StatePublished - Jun 1992

ASJC Scopus subject areas

  • Neuroscience(all)


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