Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014

Md Zakiul Hassan, Hossain M.S. Sazzad, Stephen P. Luby, Katharine Sturm-Ramirez, Mejbah Uddin Bhuiyan, Mohammed Ziaur Rahman, Md Muzahidul Islam, Ute Ströher, Sharmin Sultana, Mohammad Abdullah Heel Kafi, Peter Daszak, Mahmudur Rahman, Emily Gurley

Research output: Contribution to journalArticle

Abstract

Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we collected 1 swab sample from 5 surfaces near NiV-infected patients and tested surface and oral swab samples by real-time reverse transcription PCR for NiV RNA. We identified 16 Nipah patients; 12 cases were laboratory-confirmed and 4 probable. Of the 12 laboratory-confirmed cases, 10 showed NiV RNA in oral swab specimens. We obtained surface swab samples for 6 Nipah patients; 5 had evidence of NiV RNA on >1 surface: 4 patients contaminated towels, 3 bed sheets, and 1 the bed rail. Patients with NiV RNA in oral swab samples were significantly more likely than other Nipah patients to die. To reduce the risk for fomite transmission of NiV, infection control should target hospital surfaces.

Original languageEnglish (US)
Pages (from-to)15-21
Number of pages7
JournalEmerging Infectious Diseases
Volume24
Issue number1
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

Fingerprint

Nipah Virus
Bangladesh
Disease Outbreaks
RNA
Fomites
Virus Diseases
Infection Control
Caregivers
Reverse Transcription
Viruses
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Hassan, M. Z., Sazzad, H. M. S., Luby, S. P., Sturm-Ramirez, K., Bhuiyan, M. U., Rahman, M. Z., ... Gurley, E. (2018). Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014. Emerging Infectious Diseases, 24(1), 15-21. https://doi.org/10.3201/eid2401.161758

Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014. / Hassan, Md Zakiul; Sazzad, Hossain M.S.; Luby, Stephen P.; Sturm-Ramirez, Katharine; Bhuiyan, Mejbah Uddin; Rahman, Mohammed Ziaur; Islam, Md Muzahidul; Ströher, Ute; Sultana, Sharmin; Kafi, Mohammad Abdullah Heel; Daszak, Peter; Rahman, Mahmudur; Gurley, Emily.

In: Emerging Infectious Diseases, Vol. 24, No. 1, 01.01.2018, p. 15-21.

Research output: Contribution to journalArticle

Hassan, MZ, Sazzad, HMS, Luby, SP, Sturm-Ramirez, K, Bhuiyan, MU, Rahman, MZ, Islam, MM, Ströher, U, Sultana, S, Kafi, MAH, Daszak, P, Rahman, M & Gurley, E 2018, 'Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014', Emerging Infectious Diseases, vol. 24, no. 1, pp. 15-21. https://doi.org/10.3201/eid2401.161758
Hassan MZ, Sazzad HMS, Luby SP, Sturm-Ramirez K, Bhuiyan MU, Rahman MZ et al. Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014. Emerging Infectious Diseases. 2018 Jan 1;24(1):15-21. https://doi.org/10.3201/eid2401.161758
Hassan, Md Zakiul ; Sazzad, Hossain M.S. ; Luby, Stephen P. ; Sturm-Ramirez, Katharine ; Bhuiyan, Mejbah Uddin ; Rahman, Mohammed Ziaur ; Islam, Md Muzahidul ; Ströher, Ute ; Sultana, Sharmin ; Kafi, Mohammad Abdullah Heel ; Daszak, Peter ; Rahman, Mahmudur ; Gurley, Emily. / Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014. In: Emerging Infectious Diseases. 2018 ; Vol. 24, No. 1. pp. 15-21.
@article{3848cb971faf46c2878bf0a7f75ac54a,
title = "Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014",
abstract = "Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we collected 1 swab sample from 5 surfaces near NiV-infected patients and tested surface and oral swab samples by real-time reverse transcription PCR for NiV RNA. We identified 16 Nipah patients; 12 cases were laboratory-confirmed and 4 probable. Of the 12 laboratory-confirmed cases, 10 showed NiV RNA in oral swab specimens. We obtained surface swab samples for 6 Nipah patients; 5 had evidence of NiV RNA on >1 surface: 4 patients contaminated towels, 3 bed sheets, and 1 the bed rail. Patients with NiV RNA in oral swab samples were significantly more likely than other Nipah patients to die. To reduce the risk for fomite transmission of NiV, infection control should target hospital surfaces.",
author = "Hassan, {Md Zakiul} and Sazzad, {Hossain M.S.} and Luby, {Stephen P.} and Katharine Sturm-Ramirez and Bhuiyan, {Mejbah Uddin} and Rahman, {Mohammed Ziaur} and Islam, {Md Muzahidul} and Ute Str{\"o}her and Sharmin Sultana and Kafi, {Mohammad Abdullah Heel} and Peter Daszak and Mahmudur Rahman and Emily Gurley",
year = "2018",
month = "1",
day = "1",
doi = "10.3201/eid2401.161758",
language = "English (US)",
volume = "24",
pages = "15--21",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "1",

}

TY - JOUR

T1 - Nipah virus contamination of hospital surfaces during outbreaks, Bangladesh, 2013-2014

AU - Hassan, Md Zakiul

AU - Sazzad, Hossain M.S.

AU - Luby, Stephen P.

AU - Sturm-Ramirez, Katharine

AU - Bhuiyan, Mejbah Uddin

AU - Rahman, Mohammed Ziaur

AU - Islam, Md Muzahidul

AU - Ströher, Ute

AU - Sultana, Sharmin

AU - Kafi, Mohammad Abdullah Heel

AU - Daszak, Peter

AU - Rahman, Mahmudur

AU - Gurley, Emily

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we collected 1 swab sample from 5 surfaces near NiV-infected patients and tested surface and oral swab samples by real-time reverse transcription PCR for NiV RNA. We identified 16 Nipah patients; 12 cases were laboratory-confirmed and 4 probable. Of the 12 laboratory-confirmed cases, 10 showed NiV RNA in oral swab specimens. We obtained surface swab samples for 6 Nipah patients; 5 had evidence of NiV RNA on >1 surface: 4 patients contaminated towels, 3 bed sheets, and 1 the bed rail. Patients with NiV RNA in oral swab samples were significantly more likely than other Nipah patients to die. To reduce the risk for fomite transmission of NiV, infection control should target hospital surfaces.

AB - Nipah virus (NiV) has been transmitted from patient to caregivers in Bangladesh presumably through oral secretions. We aimed to detect whether NiV-infected patients contaminate hospital surfaces with the virus. During December 2013-April 2014, we collected 1 swab sample from 5 surfaces near NiV-infected patients and tested surface and oral swab samples by real-time reverse transcription PCR for NiV RNA. We identified 16 Nipah patients; 12 cases were laboratory-confirmed and 4 probable. Of the 12 laboratory-confirmed cases, 10 showed NiV RNA in oral swab specimens. We obtained surface swab samples for 6 Nipah patients; 5 had evidence of NiV RNA on >1 surface: 4 patients contaminated towels, 3 bed sheets, and 1 the bed rail. Patients with NiV RNA in oral swab samples were significantly more likely than other Nipah patients to die. To reduce the risk for fomite transmission of NiV, infection control should target hospital surfaces.

UR - http://www.scopus.com/inward/record.url?scp=85038821679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85038821679&partnerID=8YFLogxK

U2 - 10.3201/eid2401.161758

DO - 10.3201/eid2401.161758

M3 - Article

VL - 24

SP - 15

EP - 21

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 1

ER -