Nifedipine in Unstable Angina

Robert L. Feldman, Carl J. Pepine, C. Richard Conti, Peter R. Lichtenthal, Jerod M. Loeb, John H. Sanders, Gary Gerstenblith, Pamela Ouyang, Stephen C. Achuff, Bernadine H. Bulkley, Lewis C. Becker, E. David Mellits, Kenneth L. Baughman, James L. Weiss, John T. Flaherty, Clayton H. Kallman, Michaelene Llewellyn, Myron L. Weisfeldt

Research output: Contribution to journalLetterpeer-review

Abstract

To the Editor: The article by Gerstenblith and his colleagues (April 15 issue), comparing the use of nifedipine and placebo in patients with unstable angina admitted to a coronary-care unit,* is an important contribution to the treatment of this subgroup of patients with angina at rest. These patients had a moderate but significant reduction in ischemia-related events (sudden death, myocardial infarction, and bypass surgery) when nifedipine was added to long-acting nitrate and propranolol treatment. Analysis of the data suggests two potentially important points not discussed by the authors. First of all, although the apparent benefit of nifedipine therapy was shown.

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Volume307
Issue number10
DOIs
StatePublished - Sep 2 1982

ASJC Scopus subject areas

  • Medicine(all)

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