Nifedipine in the prophylaxis of classic migraine: A crossover, double-masked, placebo-controlled study of headache frequency and side effects

J. C. McArthur, K. Marek, A. Pestronk, J. McArthur

Research output: Contribution to journalArticle


Twenty-four patients with classic migraine attacks were treated with either nifedipine or placebo for up to 12 weeks. No significant differences were observed between the nifedipine (2.1 ± 0.2) and placebo (2.3 ± 0.2) treatment groups in the monthly frequency of headaches. However, the incidence of side effects was significantly greater (p < 0.001) in the nifedipine (54% of patients) than in the placebo (8% of patients) treatment groups.

Original languageEnglish (US)
Pages (from-to)284-286
Number of pages3
Issue number2
StatePublished - Feb 1989


ASJC Scopus subject areas

  • Clinical Neurology

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