New turf for CFP/YFP FRET imaging of membrane signaling molecules

Jenafer Evans, David T. Yue

Research output: Contribution to journalArticle

Abstract

TIRF microscopy can be used in conjunction with CFP/YFP FRET to detect movements of the cytoplasmic tails of GIRK channels (Riven et al., this issue of Neuron). This innovative combination of techniques allows molecular resolution of small motions underlying ion channel activation by G proteins and will likely find widespread use for study of membrane-associated molecules.

Original languageEnglish (US)
Pages (from-to)145-147
Number of pages3
JournalNeuron
Volume38
Issue number2
DOIs
StatePublished - Apr 24 2003

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Ion Channels
GTP-Binding Proteins
Microscopy
Neurons
Membranes

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

New turf for CFP/YFP FRET imaging of membrane signaling molecules. / Evans, Jenafer; Yue, David T.

In: Neuron, Vol. 38, No. 2, 24.04.2003, p. 145-147.

Research output: Contribution to journalArticle

Evans, Jenafer ; Yue, David T. / New turf for CFP/YFP FRET imaging of membrane signaling molecules. In: Neuron. 2003 ; Vol. 38, No. 2. pp. 145-147.
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