New turf for CFP/YFP FRET imaging of membrane signaling molecules

Jenafer Evans, David T. Yue

Research output: Contribution to journalReview articlepeer-review

Abstract

TIRF microscopy can be used in conjunction with CFP/YFP FRET to detect movements of the cytoplasmic tails of GIRK channels (Riven et al., this issue of Neuron). This innovative combination of techniques allows molecular resolution of small motions underlying ion channel activation by G proteins and will likely find widespread use for study of membrane-associated molecules.

Original languageEnglish (US)
Pages (from-to)145-147
Number of pages3
JournalNeuron
Volume38
Issue number2
DOIs
StatePublished - Apr 24 2003

ASJC Scopus subject areas

  • Neuroscience(all)

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