New Tools for Laparoscopic Division of the Pancreas: A Comparative Animal Study

Eric J. Hanly, Mario Mendoza-Sagaon, Jeffrey M. Hardacre, Kazunori Murata, Tracie E. Bunton, Karen Herreman-Suquet, Benjamin K. Poulose, Mark A. Talamini

Research output: Contribution to journalArticlepeer-review


We tested the hypothesis that the pancreas can be safely divided laparoscopically using non-suture devices. Twelve pigs were randomized into 4 groups: 1) laparoscopic distal pancreatectomy (LDP) using an ultrasonic scalpel; 2) LDP using an ultrasonic scalpel with pancreatic stump suture reinforcement; 3) LDP using a 35-mm laparoscopic linear vascular stapler; 4) LDP using a prototype 35-mm radio-frequency laparoscopic linear vascular stapler. There were no serious complications related to distal pancreatectomy. All groups gained weight by postoperative day (POD) 14. Serum amylase, glucose, electrolytes and total bilirubin levels were measured preoperatively and on POD 1, 3, 7, and 14, and peripancreatic peritoneal fluid amylase levels were measured on POD 7 and 14; all remained normal in all groups. Fewer adhesions to the pancreatic stump were found in the ultrasonic scalpel groups as compared with the stapler groups. Ultrasonic dissection may be the superior means of laparoscopic transection of the pancreas.

Original languageEnglish (US)
Pages (from-to)53-60
Number of pages8
JournalSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
Issue number2
StatePublished - Apr 1 2004


  • Laparoscopic distal pancreatectomy
  • Laparoscopic linear stapler
  • Laparoscopy
  • Pancreatectomy
  • Radio-frequency stapler
  • Ultrasonic scalpel

ASJC Scopus subject areas

  • Surgery


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