New insights into pancreatic cancer biology

M. Hidalgo

Research output: Contribution to journalArticlepeer-review

Abstract

Pancreatic cancer remains a devastating disease. Over the last few years, there have been important advances in the molecular and biological understanding of pancreatic cancer. This included understanding of the genomic complexity of the disease, the role of pancreatic cancer stem cells, the relevance of the tumor microenvironment, and the unique metabolic adaptation of pancreas cancer cells to obtain nutrients under hypoxic environment. In this paper, we review the most salient developments in these few areas.

Original languageEnglish (US)
Article numbermds313
Pages (from-to)x135-x138
JournalAnnals of Oncology
Volume23
Issue numberSUPPL. 10
DOIs
StatePublished - Sep 2012

Keywords

  • Cancer stem cells
  • Genomics
  • Pancreatic cancer
  • Stroma

ASJC Scopus subject areas

  • Hematology
  • Oncology

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