New Insights in the Diagnosis and Treatment of Heart Failure

Giulio Agnetti, Massimo F. Piepoli, Giuseppe Siniscalchi, Francesco Nicolini

Research output: Contribution to journalReview article

Abstract

Cardiovascular disease is the leading cause of mortality in the US and in westernized countries with ischemic heart disease accounting for the majority of these deaths. Paradoxically, the improvements in the medical and surgical treatments of acute coronary syndrome are leading to an increasing number of "survivors" who are then developing heart failure. Despite considerable advances in its management, the gold standard for the treatment of end-stage heart failure patients remains heart transplantation. Nevertheless, this procedure can be offered only to a small percentage of patients who could benefit from a new heart due to the limited availability of donor organs. The aim of this review is to evaluate the safety and efficacy of innovative approaches in the diagnosis and treatment of patients refractory to standard medical therapy and excluded from cardiac transplantation lists.

LanguageEnglish (US)
Article number265260
JournalBioMed Research International
Volume2015
DOIs
StatePublished - 2015

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Treatment Failure
Heart Failure
Heart Transplantation
Therapeutics
Acute Coronary Syndrome
Myocardial Ischemia
Survivors
Cardiovascular Diseases
Refractory materials
Tissue Donors
Safety
Mortality
Availability

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Agnetti, G., Piepoli, M. F., Siniscalchi, G., & Nicolini, F. (2015). New Insights in the Diagnosis and Treatment of Heart Failure. BioMed Research International, 2015, [265260]. DOI: 10.1155/2015/265260

New Insights in the Diagnosis and Treatment of Heart Failure. / Agnetti, Giulio; Piepoli, Massimo F.; Siniscalchi, Giuseppe; Nicolini, Francesco.

In: BioMed Research International, Vol. 2015, 265260, 2015.

Research output: Contribution to journalReview article

Agnetti G, Piepoli MF, Siniscalchi G, Nicolini F. New Insights in the Diagnosis and Treatment of Heart Failure. BioMed Research International. 2015;2015. 265260. Available from, DOI: 10.1155/2015/265260
Agnetti, Giulio ; Piepoli, Massimo F. ; Siniscalchi, Giuseppe ; Nicolini, Francesco. / New Insights in the Diagnosis and Treatment of Heart Failure. In: BioMed Research International. 2015 ; Vol. 2015.
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