New goals for the U.S. Human Genome Project: 1998-2003

Francis S. Collins, Ari Patrinos, Elke Jordan, Aravinda Chakravarti, Raymond Gesteland, Le Roy Walters

Research output: Contribution to journalReview article


The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a 'working draft' of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.

Original languageEnglish (US)
Pages (from-to)682-689
Number of pages8
Issue number5389
StatePublished - Oct 23 1998

ASJC Scopus subject areas

  • General

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    Collins, F. S., Patrinos, A., Jordan, E., Chakravarti, A., Gesteland, R., & Walters, L. R. (1998). New goals for the U.S. Human Genome Project: 1998-2003. Science, 282(5389), 682-689.