New drugs and novel targets for treatment of invasive fungal infections in patients with cancer

Christine C. Chiou, Andreas H. Groll, Thomas J. Walsh

Research output: Contribution to journalArticlepeer-review

Abstract

Invasive fungal infections have emerged as important causes of morbidity and mortality in profoundly immuno-compromised patients with cancer. Current treatment strategies for these infections are limited by antifungal resistance, toxicity, drug interactions, and expense. In order to overcome these limitations, new antifungal compounds are being developed, which may improve our therapeutic armamentarium for prevention and treatment of invasive mycoses in high-risk patients with neoplastic diseases.

Original languageEnglish (US)
Pages (from-to)120-135
Number of pages16
JournalOncologist
Volume5
Issue number2
DOIs
StatePublished - 2000

Keywords

  • Echinocondins
  • Posaconazole
  • Ravuconazole
  • Triazoles
  • Voriconazole

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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