New developments in the use of tricyclic antidepressants for the management of pain

Steven P. Cohen, Salahadin Abdi

Research output: Contribution to journalReview article

Abstract

In recent years, tricyclic antidepressant drugs have experienced a resurgence in their use as valuable pharmacological tools in the treatment of pain. Along with the evolution in our understanding of their analgesic mechanisms of action, there have been concurrent breakthroughs regarding their indications for use and modes of administration. This review focuses on recent advances in our understanding of how antidepressant drugs exert their antinociceptive effects, and new developments regarding their clinical application.

Original languageEnglish (US)
Pages (from-to)505-511
Number of pages7
JournalCurrent Opinion in Anaesthesiology
Volume14
Issue number5
DOIs
StatePublished - Oct 22 2001
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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