New delivery systems for brain tumor therapy

E. P. Sipos, H. Brem

Research output: Contribution to journalReview articlepeer-review

Abstract

Therapy of brain tumors has been limited by lack of effective methods of drug delivery. Systemic administration often fails to achieve therapeutic concentrations of drugs within intracranial tumors despite toxic systemic levels. This article discusses new methods for delivering therapeutic agents to brain tumors, including intra-arterial, intrathecal, intraventricular, and interstitial administration techniques.

Original languageEnglish (US)
Pages (from-to)813-825
Number of pages13
JournalNeurologic clinics
Volume13
Issue number4
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Clinical Neurology

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