New approaches for measuring changes in the cortical surface using an automatic reconstruction algorithm

Dzung L. Pham, Xiao Han, Maryam E. Rettmann, Chenyang Xu, Duygu Tosun, Susan M. Resnick, Jerry Ladd Prince

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In previous work, the authors presented a multi-stage procedure for the semi-automatic reconstruction of the cerebral cortex from magnetic resonance images. This method suffered from several disadvantages. First, the tissue classification algorithm used can be sensitive to noise within the image. Second, manual interaction was required for masking out undesired regions of the brain image, such as the ventricles and putamen. Third, iterated median filters were used to perform a topology correction on the initial cortical surface, resulting in an overly smoothed initial surface. Finally, the deformable surface used to converge to the cortex had difficulty capturing narrow gyri. In this work, all four disadvantages of the procedure have been addressed. A more robust tissue classification algorithm is employed and the manual masking step is replaced by an automatic method involving level set deformable models. Instead of iterated median filters, an algorithm developed specifically for topology correction is used. The last disadvantage is addressed using an algorithm that artificially separates adjacent sulcal banks. The new procedure is more automated but also more accurate than the previous one. Its utility is demonstrated by performing a preliminary study on data from the Baltimore Longitudinal Study of Aging.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsM. Sonka, J. Michael Fitzpatrick
Pages191-200
Number of pages10
Volume4684 I
DOIs
StatePublished - 2002
EventMedical Imaging 2002: Image Processing - San Diego, CA, United States
Duration: Feb 24 2002Feb 28 2002

Other

OtherMedical Imaging 2002: Image Processing
CountryUnited States
CitySan Diego, CA
Period2/24/022/28/02

Fingerprint

Median filters
masking
topology
Topology
cerebral cortex
Tissue
filters
cortexes
Magnetic resonance
brain
magnetic resonance
Brain
Aging of materials
interactions

Keywords

  • Cerebral cortex
  • Deformable models
  • Fuzzy clustering
  • Image segmentation
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Pham, D. L., Han, X., Rettmann, M. E., Xu, C., Tosun, D., Resnick, S. M., & Prince, J. L. (2002). New approaches for measuring changes in the cortical surface using an automatic reconstruction algorithm. In M. Sonka, & J. Michael Fitzpatrick (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4684 I, pp. 191-200) https://doi.org/10.1117/12.467145

New approaches for measuring changes in the cortical surface using an automatic reconstruction algorithm. / Pham, Dzung L.; Han, Xiao; Rettmann, Maryam E.; Xu, Chenyang; Tosun, Duygu; Resnick, Susan M.; Prince, Jerry Ladd.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / M. Sonka; J. Michael Fitzpatrick. Vol. 4684 I 2002. p. 191-200.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Pham, DL, Han, X, Rettmann, ME, Xu, C, Tosun, D, Resnick, SM & Prince, JL 2002, New approaches for measuring changes in the cortical surface using an automatic reconstruction algorithm. in M Sonka & J Michael Fitzpatrick (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4684 I, pp. 191-200, Medical Imaging 2002: Image Processing, San Diego, CA, United States, 2/24/02. https://doi.org/10.1117/12.467145
Pham DL, Han X, Rettmann ME, Xu C, Tosun D, Resnick SM et al. New approaches for measuring changes in the cortical surface using an automatic reconstruction algorithm. In Sonka M, Michael Fitzpatrick J, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4684 I. 2002. p. 191-200 https://doi.org/10.1117/12.467145
Pham, Dzung L. ; Han, Xiao ; Rettmann, Maryam E. ; Xu, Chenyang ; Tosun, Duygu ; Resnick, Susan M. ; Prince, Jerry Ladd. / New approaches for measuring changes in the cortical surface using an automatic reconstruction algorithm. Proceedings of SPIE - The International Society for Optical Engineering. editor / M. Sonka ; J. Michael Fitzpatrick. Vol. 4684 I 2002. pp. 191-200
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