Abstract
Advances in nanotechnology have the potential to dramatically enhance the detection of neurologic diseases with targeted contrast agents and to facilitate the delivery of focused therapies to the central nervous system. We present the physicochemical rationale for their use, applications in animal models, and ongoing clinical trials using these approaches. We highlight advances in the use of nanoparticles applied to brain tumor imaging, tumor angiogenesis, neurodegeneration, grafted stem cells, and neuroprogenitor cells.
Original language | English (US) |
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Pages (from-to) | 1246-1253 |
Number of pages | 8 |
Journal | American Journal of Neuroradiology |
Volume | 35 |
Issue number | 7 |
DOIs | |
State | Published - Jul 2014 |
Externally published | Yes |
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology