New and old agents in diarrhea: A prospective study of an indigenous adult African population

D. P. Hansen, R. G. Kaminsky, L. R. Bagg, A. Z. Kapikian, R. C. Slack, D. A. Sack

Research output: Contribution to journalArticlepeer-review

Abstract

We conducted a prospective study of 77 indigenous African adults with acute diarrhea seeking care at the major hospital in Nairobi, Kenya, to determine the major pathogens responsible for this syndrome in adults. Fecal and blood specimens were collected and examined for enteric bacterial pathogens, viruses, and parasites. In 13 (26%) inpatients and 11 (49%) outpatients Shigella was found, and heat-labile and heat-stable forms of enterotoxigenic Escherichia coli were found in 9 (18%) inpatients and 1 (4%) outpatient. Human reovirus-like agent titers rose significantly in another 3 (6%). Amebic dysentery was not seen although hemagglutination-inhibition tests for invasive Entamoeba histolytica were positive in 4 inpatients. An etiologic agent was found in 65% of patients.

Original languageEnglish (US)
Pages (from-to)609-615
Number of pages7
JournalUnknown Journal
Volume27
Issue number3
DOIs
StatePublished - Jan 1 1978
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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