New and emerging risk factors for coronary heart disease

Ehimare Akhabue; Jeffrey Thiboutot; Jeh Wei Cheng; Timothy J. Vittorio; Georgios Christodoulidis; Kathleen M. Grady; Stamatios Lerakis; Constantine E. Kosmas

doi:10.1097/MAJ.0b013e31828aab45

New and emerging risk factors for coronary heart disease

Ehimare Akhabue, Jeffrey Thiboutot, Jeh Wei Cheng, Timothy J. Vittorio, Georgios Christodoulidis, Kathleen M. Grady, Stamatios Lerakis, Constantine E. Kosmas

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

Abstract

Coronary heart disease (CHD) is one of the leading causes of death in the United States. Traditional risk factors such as family history, hypertension, hypercholesterolemia, diabetes mellitus and smoking cannot account for the entire risk for incident coronary events. Several other potential risk factors have been identified in an effort to improve risk assessment for CHD. This article reviews the current evidence on new and emerging risk factors for CHD and their current utility in screening, specifically focusing on coronary artery calcium score, C-reactive protein, lipoprotein (a), carotid intima-media thickness, homocysteine, lipoprotein-associated phospholipase A2, as well as high-density lipoprotein functionality.

Original language	English (US)
Pages (from-to)	151-158
Number of pages	8
Journal	American Journal of the Medical Sciences
Volume	347
Issue number	2
DOIs	https://doi.org/10.1097/MAJ.0b013e31828aab45
State	Published - 2014
Externally published	Yes

Keywords

C-reactive protein
Carotid intimal media thickness
Coronary artery calcium score
Coronary heart disease
Lipoprotein (a)

ASJC Scopus subject areas

General Medicine

Access to Document

10.1097/MAJ.0b013e31828aab45

Cite this

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title = "New and emerging risk factors for coronary heart disease",

abstract = "Coronary heart disease (CHD) is one of the leading causes of death in the United States. Traditional risk factors such as family history, hypertension, hypercholesterolemia, diabetes mellitus and smoking cannot account for the entire risk for incident coronary events. Several other potential risk factors have been identified in an effort to improve risk assessment for CHD. This article reviews the current evidence on new and emerging risk factors for CHD and their current utility in screening, specifically focusing on coronary artery calcium score, C-reactive protein, lipoprotein (a), carotid intima-media thickness, homocysteine, lipoprotein-associated phospholipase A2, as well as high-density lipoprotein functionality.",

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author = "Ehimare Akhabue and Jeffrey Thiboutot and Cheng, {Jeh Wei} and Vittorio, {Timothy J.} and Georgios Christodoulidis and Grady, {Kathleen M.} and Stamatios Lerakis and Kosmas, {Constantine E.}",

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AU - Akhabue, Ehimare

AU - Thiboutot, Jeffrey

AU - Cheng, Jeh Wei

AU - Vittorio, Timothy J.

AU - Christodoulidis, Georgios

AU - Grady, Kathleen M.

AU - Lerakis, Stamatios

AU - Kosmas, Constantine E.

PY - 2014

Y1 - 2014

N2 - Coronary heart disease (CHD) is one of the leading causes of death in the United States. Traditional risk factors such as family history, hypertension, hypercholesterolemia, diabetes mellitus and smoking cannot account for the entire risk for incident coronary events. Several other potential risk factors have been identified in an effort to improve risk assessment for CHD. This article reviews the current evidence on new and emerging risk factors for CHD and their current utility in screening, specifically focusing on coronary artery calcium score, C-reactive protein, lipoprotein (a), carotid intima-media thickness, homocysteine, lipoprotein-associated phospholipase A2, as well as high-density lipoprotein functionality.

AB - Coronary heart disease (CHD) is one of the leading causes of death in the United States. Traditional risk factors such as family history, hypertension, hypercholesterolemia, diabetes mellitus and smoking cannot account for the entire risk for incident coronary events. Several other potential risk factors have been identified in an effort to improve risk assessment for CHD. This article reviews the current evidence on new and emerging risk factors for CHD and their current utility in screening, specifically focusing on coronary artery calcium score, C-reactive protein, lipoprotein (a), carotid intima-media thickness, homocysteine, lipoprotein-associated phospholipase A2, as well as high-density lipoprotein functionality.

KW - C-reactive protein

KW - Carotid intimal media thickness

KW - Coronary artery calcium score

KW - Coronary heart disease

KW - Lipoprotein (a)

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New and emerging risk factors for coronary heart disease

Abstract

Keywords

ASJC Scopus subject areas

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